ATG7 anticorps (AA 652-669)

N° du produit ABIN3030040

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG7 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATG7 anticorps (AA 652-669) (ABIN3030040)

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATG7 anticorps

Épitope: AA 652-669

Purification: Antigen affinity

Immunogène: Amino acids 652-669 (KVLDQYEREGFNFLAKVF-human) were used as the immunogen for this ATG7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titration of the ATG7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the ATG7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ATG7

Antigène: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Autre désignation: ATG7

Sujet: Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, the protein can regulate p53-dependent cell cycle and cell death pathways.

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy